Evidence that a Panel of Neurodegeneration Biomarkers Predicts Vasospasm, Infarction, and Outcome in Aneurysmal Subarachnoid Hemorrhage

Robert Siman; Nicholas Giovannone; Nikhil Toraskar; Suzanne Frangos; Sherman C. Stein; Joshua M. Levine; Monisha A. Kumar

doi:10.1371/journal.pone.0028938

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Research Article

Evidence that a Panel of Neurodegeneration Biomarkers Predicts Vasospasm, Infarction, and Outcome in Aneurysmal Subarachnoid Hemorrhage

Robert Siman ,

* E-mail: siman@mail.med.upenn.edu

Affiliation Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Nicholas Giovannone,

Affiliation Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Nikhil Toraskar,

Affiliation Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Suzanne Frangos,

Affiliation Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Sherman C. Stein,

Affiliation Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Joshua M. Levine,

Affiliations Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Anesthesiology and Critical Care, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Monisha A. Kumar

Affiliations Department of Neurosurgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Anesthesiology and Critical Care, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Evidence that a Panel of Neurodegeneration Biomarkers Predicts Vasospasm, Infarction, and Outcome in Aneurysmal Subarachnoid Hemorrhage

Robert Siman,
Nicholas Giovannone,
Nikhil Toraskar,
Suzanne Frangos,
Sherman C. Stein,
Joshua M. Levine,
Monisha A. Kumar

Published: December 9, 2011
https://doi.org/10.1371/journal.pone.0028938

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Biomarkers
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Cerebrospinal fluid
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Brain damage
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Infarction
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Enzyme-linked immunoassays
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