Checkpoint Signaling, Base Excision Repair, and PARP Promote Survival of Colon Cancer Cells Treated with 5-Fluorodeoxyuridine but Not 5-Fluorouracil

Open Access

Peer-reviewed

Research Article

Liyi Geng,

Affiliation Division of Oncology Research, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
⨯
Amelia M. Huehls,

Affiliations Division of Oncology Research, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
⨯
Jill M. Wagner,

Affiliation Division of Oncology Research, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
⨯
Catherine J. Huntoon,

Affiliation Division of Oncology Research, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
⨯
Larry M. Karnitz

* E-mail: karnitz.larry@mayo.edu

Affiliations Division of Oncology Research, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America, Department of Radiation Oncology, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
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Cancer treatment
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Small interfering RNA
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DNA repair
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Transfection
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