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Open Access
Peer-reviewed
Research Article
Differences in Genotype and Virulence among Four Multidrug-Resistant Streptococcus pneumoniae Isolates Belonging to the PMEN1 Clone
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N. Luisa Hiller,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Rory A. Eutsey,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Evan Powell,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Joshua P. Earl,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Benjamin Janto,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Darren P. Martin,
Affiliation Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
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Suzanne Dawid,
Affiliation Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, United States of America
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Azad Ahmed,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Mark J. Longwell,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Margaret E. Dahlgren,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Suzanne Ezzo,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Herve Tettelin,
Affiliation Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Sean C. Daugherty,
Affiliation Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Timothy J. Mitchell,
Affiliation Institute of Infection, Immunology and Inflammation, University of Glasgow, Glasgow, Scotland
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Todd A. Hillman,
Affiliation Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America
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Farrel J. Buchinsky,
Affiliations Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America, Department of Microbiology and Immunology, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America, Department of Otolaryngology/Head and Neck Surgery, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America
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Alexander Tomasz,
Affiliation Rockefeller University, New York, New York, United States of America
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Herminia de Lencastre,
Affiliations Rockefeller University, New York, New York, United States of America, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal
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Raquel Sá-Leão,
Affiliation Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal
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J. Christopher Post,
Affiliations Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America, Department of Microbiology and Immunology, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America, Department of Otolaryngology/Head and Neck Surgery, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America
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Fen Z. Hu,
Affiliations Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America, Department of Microbiology and Immunology, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America, Department of Otolaryngology/Head and Neck Surgery, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America
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Garth D. Ehrlich
* E-mail: gehrlich@wpahs.org
Affiliations Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America, Department of Microbiology and Immunology, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America, Department of Otolaryngology/Head and Neck Surgery, Drexel University College of Medicine, Allegheny Campus, Pittsburgh, Pennsylvania, United States of America
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Differences in Genotype and Virulence among Four Multidrug-Resistant Streptococcus pneumoniae Isolates Belonging to the PMEN1 Clone
- N. Luisa Hiller,
- Rory A. Eutsey,
- Evan Powell,
- Joshua P. Earl,
- Benjamin Janto,
- Darren P. Martin,
- Suzanne Dawid,
- Azad Ahmed,
- Mark J. Longwell,
- Margaret E. Dahlgren
- Published: December 19, 2011
- https://doi.org/10.1371/journal.pone.0028850