Identification of Fluorescent Compounds with Non-Specific Binding Property via High Throughput Live Cell Microscopy

Sangeeta Nath; Virginia A. Spencer; Ju Han; Hang Chang; Kai Zhang; Gerald V. Fontenay; Charles Anderson; Joel M. Hyman; Marit Nilsen-Hamilton; Young-Tae Chang; Bahram Parvin

doi:10.1371/journal.pone.0028802

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Open Access

Peer-reviewed

Research Article

Identification of Fluorescent Compounds with Non-Specific Binding Property via High Throughput Live Cell Microscopy

Sangeeta Nath,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Virginia A. Spencer,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Ju Han,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Hang Chang,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Kai Zhang,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Gerald V. Fontenay,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Charles Anderson,

Affiliation Energy Biosciences Institute, University of California, Berkeley, California, United States of America
⨯
Joel M. Hyman,

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Marit Nilsen-Hamilton,

Affiliation Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, United States of America
⨯
Young-Tae Chang,

Affiliation Department of Chemistry and MedChem Program of Life Sciences Institute, National University of Singapore, and Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore
⨯
Bahram Parvin

* E-mail: b_parvin@lbl.gov

Affiliation Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯

Identification of Fluorescent Compounds with Non-Specific Binding Property via High Throughput Live Cell Microscopy

Sangeeta Nath,
Virginia A. Spencer,
Ju Han,
Hang Chang,
Kai Zhang,
Gerald V. Fontenay,
Charles Anderson,
Joel M. Hyman,
Marit Nilsen-Hamilton,
Young-Tae Chang

Published: January 5, 2012
https://doi.org/10.1371/journal.pone.0028802

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