Missense Mutation in the Second RNA Binding Domain Reveals a Role for Prkra (PACT/RAX) during Skull Development

Benjamin K. Dickerman; Christine L. White; Claire Chevalier; Valérie Nalesso; Cyril Charles; Sophie Fouchécourt; Florian Guillou; Laurent Viriot; Ganes C. Sen; Yann Hérault

doi:10.1371/journal.pone.0028537

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Peer-reviewed

Research Article

Missense Mutation in the Second RNA Binding Domain Reveals a Role for Prkra (PACT/RAX) during Skull Development

Benjamin K. Dickerman,

Affiliations Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Graduate Program in Molecular Virology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Christine L. White,

Affiliation Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Claire Chevalier,

Affiliation Institut de Génétique Biologie Moléculaire et Cellulaire and Institut Clinique de la Souris, IGBMC/ICS, CNRS, INSERM, UMR7104, UMR964, Université de Strasbourg, Illkirch, France
⨯
Valérie Nalesso,

Affiliation Institut de Génétique Biologie Moléculaire et Cellulaire and Institut Clinique de la Souris, IGBMC/ICS, CNRS, INSERM, UMR7104, UMR964, Université de Strasbourg, Illkirch, France
⨯
Cyril Charles,

Affiliation Team Evo-Devo of Vertebrate Dentition, Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS, Université de Lyon, Lyon, France
⨯
Sophie Fouchécourt,

Affiliation Physiologie de la Reproduction et des Comportements INRA/CNRS/Université de Tours/Haras Nationaux, UMR 6175 Centre de Recherche de Tours, Nouzilly, France
⨯
Florian Guillou,

Affiliation Physiologie de la Reproduction et des Comportements INRA/CNRS/Université de Tours/Haras Nationaux, UMR 6175 Centre de Recherche de Tours, Nouzilly, France
⨯
Laurent Viriot,

Affiliation Team Evo-Devo of Vertebrate Dentition, Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS, Université de Lyon, Lyon, France
⨯
Ganes C. Sen ,

* E-mail: seng@ccf.org

Affiliations Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Graduate Program in Molecular Virology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Yann Hérault

Affiliation Institut de Génétique Biologie Moléculaire et Cellulaire and Institut Clinique de la Souris, IGBMC/ICS, CNRS, INSERM, UMR7104, UMR964, Université de Strasbourg, Illkirch, France
⨯

Missense Mutation in the Second RNA Binding Domain Reveals a Role for Prkra (PACT/RAX) during Skull Development

Benjamin K. Dickerman,
Christine L. White,
Claire Chevalier,
Valérie Nalesso,
Cyril Charles,
Sophie Fouchécourt,
Florian Guillou,
Laurent Viriot,
Ganes C. Sen,
Yann Hérault

Published: December 14, 2011
https://doi.org/10.1371/journal.pone.0028537

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Homozygosity
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Point mutation
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L929 cells
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