Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

Man Kit Tse; Sin Kam Hui; Yinhua Yang; Si-Tao Yin; Hong-Yu Hu; Bing Zou; Benjamin Chun Yu Wong; Kong Hung Sze

doi:10.1371/journal.pone.0028511

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Peer-reviewed

Research Article

Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

Man Kit Tse ,

Contributed equally to this work with: Man Kit Tse, Sin Kam Hui

Affiliations Department of Microbiology and State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong SAR, People's Republic of China, Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Hong Kong SAR, People's Republic of China
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Sin Kam Hui ,

Contributed equally to this work with: Man Kit Tse, Sin Kam Hui

Affiliation Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Hong Kong SAR, People's Republic of China
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Yinhua Yang,

Affiliation Department of Biochemistry, Centre for Protein Science and Crystallography, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, People's Republic of China
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Si-Tao Yin,

Affiliation State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China
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Hong-Yu Hu,

Affiliation State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China
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Bing Zou,

Affiliation Department of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, People's Republic of China
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Benjamin Chun Yu Wong,

Affiliation Department of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, People's Republic of China
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Kong Hung Sze

* E-mail: khsze@hku.hk

Affiliations Department of Microbiology and State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong SAR, People's Republic of China, Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Hong Kong SAR, People's Republic of China
⨯

Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

Man Kit Tse,
Sin Kam Hui,
Yinhua Yang,
Si-Tao Yin,
Hong-Yu Hu,
Bing Zou,
Benjamin Chun Yu Wong,
Kong Hung Sze

Published: December 15, 2011
https://doi.org/10.1371/journal.pone.0028511

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