Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

Eva M. Galan-Moya; Miguel A. de la Cruz-Morcillo; Maria Llanos Valero; Juan L. Callejas-Valera; Pedro Melgar-Rojas; Javier Hernadez Losa; Mayte Salcedo; Antonio Fernández-Aramburo; Santiago Ramon y. Cajal; Ricardo Sánchez-Prieto

doi:10.1371/journal.pone.0028406

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Peer-reviewed

Research Article

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

Eva M. Galan-Moya,

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯
Miguel A. de la Cruz-Morcillo ,

Contributed equally to this work with: Miguel A. de la Cruz-Morcillo, Maria Llanos Valero

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯
Maria Llanos Valero ,

Contributed equally to this work with: Miguel A. de la Cruz-Morcillo, Maria Llanos Valero

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯
Juan L. Callejas-Valera,

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯
Pedro Melgar-Rojas,

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯
Javier Hernadez Losa,

Affiliation Pathology Department, Fundació Institut de Recerca Hospital Vall d'Hebron, Barcelona, Spain
⨯
Mayte Salcedo,

Affiliation Pathology Department, Fundació Institut de Recerca Hospital Vall d'Hebron, Barcelona, Spain
⨯
Antonio Fernández-Aramburo,

Affiliations Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain, Servicio de Oncología CHUA, Albacete, Spain
⨯
Santiago Ramon y. Cajal,

Affiliation Pathology Department, Fundació Institut de Recerca Hospital Vall d'Hebron, Barcelona, Spain
⨯
Ricardo Sánchez-Prieto

* E-mail: ricardo.sanchez@uclm.es

Affiliation Laboratorio de Oncología Molecular, Centro Regional de Investigaciones Biomédicas, PCYTA/ UCLM, Albacete, Spain
⨯

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

Eva M. Galan-Moya,
Miguel A. de la Cruz-Morcillo,
Maria Llanos Valero,
Juan L. Callejas-Valera,
Pedro Melgar-Rojas,
Javier Hernadez Losa,
Mayte Salcedo,
Antonio Fernández-Aramburo,
Santiago Ramon y. Cajal,
Ricardo Sánchez-Prieto

Published: December 2, 2011
https://doi.org/10.1371/journal.pone.0028406

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