Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning

• Julia E. Sero,

  Current address: Dynamical Cell Systems Team, Division of Cancer Biology, Institute of Cancer Research, London, United Kingdom

  Affiliation Vascular Biology Program, Departments of Pathology and Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America

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• Charles K. Thodeti,

  Current address: Department of Integrative Medical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio, United States of America

  Affiliation Vascular Biology Program, Departments of Pathology and Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America

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• Akiko Mammoto,

  Affiliation Vascular Biology Program, Departments of Pathology and Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America

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• Chris Bakal,

  Affiliation Dynamical Cell Systems Team, Division of Cancer Biology, Institute of Cancer Research, London, United Kingdom

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• Sheila Thomas,

  Affiliation Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

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• Donald E. Ingber

  * E-mail: don.ingber@wyss.harvard.edu

  Affiliations Vascular Biology Program, Departments of Pathology and Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America, Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts, United States of America, School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America

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