Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

R. Robert Vethanayagam; Nikolaos G. Almyroudis; Melissa J. Grimm; David C. Lewandowski; Christine T. N. Pham; Timothy S. Blackwell; Ruta Petraitiene; Vidmantas Petraitis; Thomas J. Walsh; Constantin F. Urban; Brahm H. Segal

doi:10.1371/journal.pone.0028149

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Open Access

Peer-reviewed

Research Article

Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

R. Robert Vethanayagam ,

Contributed equally to this work with: R. Robert Vethanayagam, Nikolaos G. Almyroudis

Affiliation Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America
⨯
Nikolaos G. Almyroudis ,

Contributed equally to this work with: R. Robert Vethanayagam, Nikolaos G. Almyroudis

Affiliations Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, United States of America
⨯
Melissa J. Grimm,

Affiliation Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America
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David C. Lewandowski,

Affiliation Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America
⨯
Christine T. N. Pham,

Affiliation Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America
⨯
Timothy S. Blackwell,

Affiliation Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Ruta Petraitiene,

Affiliation Transplantation-Oncology Infectious Diseases Program, Weill Cornell University Medical Center, New York, New York, United States of America
⨯
Vidmantas Petraitis,

Affiliation Transplantation-Oncology Infectious Diseases Program, Weill Cornell University Medical Center, New York, New York, United States of America
⨯
Thomas J. Walsh,

Affiliation Transplantation-Oncology Infectious Diseases Program, Weill Cornell University Medical Center, New York, New York, United States of America
⨯
Constantin F. Urban,

Affiliation Department of Molecular Biology, Umeå University, Umeå, Sweden
⨯
Brahm H. Segal

* E-mail: brahm.segal@roswellpark.org

Affiliations Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, United States of America, Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York, United States of America
⨯

Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

R. Robert Vethanayagam,
Nikolaos G. Almyroudis,
Melissa J. Grimm,
David C. Lewandowski,
Christine T. N. Pham,
Timothy S. Blackwell,
Ruta Petraitiene,
Vidmantas Petraitis,
Thomas J. Walsh,
Constantin F. Urban

Published: December 7, 2011
https://doi.org/10.1371/journal.pone.0028149

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