Hypochlorous Acid-Induced Heme Degradation from Lactoperoxidase as a Novel Mechanism of Free Iron Release and Tissue Injury in Inflammatory Diseases

• Carlos Eduardo A. Souza ,

  Contributed equally to this work with: Carlos Eduardo A. Souza, Dhiman Maitra

  Affiliation Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, United States of America

  ⨯
• Dhiman Maitra ,

  Contributed equally to this work with: Carlos Eduardo A. Souza, Dhiman Maitra

  Affiliation Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, United States of America

  ⨯
• Ghassan M. Saed,

  Affiliation Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, United States of America

  ⨯
• Michael P. Diamond,

  Affiliation Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, United States of America

  ⨯
• Arlindo A. Moura,

  Affiliation Federal University of Ceará, Fortaleza, Ceará, Brazil

  ⨯
• Subramaniam Pennathur,

  Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

  ⨯
• Husam M. Abu-Soud

  * E-mail: habusoud@med.wayne.edu

  Affiliations Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America

  ⨯