Ago-2-Mediated Slicer Activity Is Essential for Anti-Flaviviral Efficacy of RNAi

Shuiping Chen; Harendra S. Chahar; Sojan Abraham; Haoquan Wu; Theodore C. Pierson; Xiaozhong A. Wang; N. Manjunath

doi:10.1371/journal.pone.0027551

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Peer-reviewed

Research Article

Ago-2-Mediated Slicer Activity Is Essential for Anti-Flaviviral Efficacy of RNAi

Shuiping Chen,

Affiliation Department of Biomedical Sciences, Center of Excellence in Infectious Disease Research, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States of America
⨯
Harendra S. Chahar,

Affiliation Department of Biomedical Sciences, Center of Excellence in Infectious Disease Research, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States of America
⨯
Sojan Abraham,

Affiliation Department of Biomedical Sciences, Center of Excellence in Infectious Disease Research, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States of America
⨯
Haoquan Wu,

Affiliation Department of Biomedical Sciences, Center of Excellence in Infectious Disease Research, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States of America
⨯
Theodore C. Pierson,

Affiliation Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Xiaozhong A. Wang,

Affiliation Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois, United States of America
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N. Manjunath

* E-mail: manjunath.swamy@ttuhsc.edu

Affiliation Department of Biomedical Sciences, Center of Excellence in Infectious Disease Research, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States of America
⨯

Ago-2-Mediated Slicer Activity Is Essential for Anti-Flaviviral Efficacy of RNAi

Shuiping Chen,
Harendra S. Chahar,
Sojan Abraham,
Haoquan Wu,
Theodore C. Pierson,
Xiaozhong A. Wang,
N. Manjunath

Published: November 10, 2011
https://doi.org/10.1371/journal.pone.0027551

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