DNA Damage Stress and Inhibition of Jak2-V617F Cause Its Degradation and Synergistically Induce Apoptosis through Activation of GSK3β

Open Access

Peer-reviewed

Research Article

Toshikage Nagao,

Affiliation Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⨯
Gaku Oshikawa,

Affiliation Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⨯
Nan Wu,

Affiliation Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⨯
Tetsuya Kurosu,

Affiliation Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⨯
Osamu Miura

* E-mail: miura.hema@tmd.ac.jp

Affiliation Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⨯

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DNA damage
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Apoptosis
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Immunoprecipitation
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Immunoblotting
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293T cells
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Phosphorylation
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Transfection
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Tyrosine kinases
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