The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

Ehm A. Andersson; Marie N. Harder; Kasper Pilgaard; Charlotta Pisinger; Alena Stančáková; Johanna Kuusisto; Niels Grarup; Kristine Færch; Pernille Poulsen; Daniel R. Witte; Torben Jørgensen; Allan Vaag; Markku Laakso; Oluf Pedersen; Torben Hansen

doi:10.1371/journal.pone.0027096

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Open Access

Peer-reviewed

Research Article

The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

Ehm A. Andersson,

Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Marie N. Harder ,

* E-mail: marie.harder@sund.ku.dk

Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Kasper Pilgaard,

Affiliation Steno Diabetes Center, Gentofte, Denmark
⨯
Charlotta Pisinger,

Affiliation Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
⨯
Alena Stančáková,

Affiliation Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
⨯
Johanna Kuusisto,

Affiliation Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
⨯
Niels Grarup,

Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Kristine Færch,

Affiliation Steno Diabetes Center, Gentofte, Denmark
⨯
Pernille Poulsen,

Affiliation Steno Diabetes Center, Gentofte, Denmark
⨯
Daniel R. Witte,

Affiliation Steno Diabetes Center, Gentofte, Denmark
⨯
Torben Jørgensen,

Affiliations Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark, Department of Public Health, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
⨯
Allan Vaag,

Affiliations Steno Diabetes Center, Gentofte, Denmark, Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark
⨯
Markku Laakso,

Affiliation Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
⨯
Oluf Pedersen,

Affiliations Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Institute of Biomedical Science, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Sciences, University of Aarhus, Aarhus, Denmark, Hagedorn Research Institute, Gentofte, Denmark
⨯
Torben Hansen

Affiliations Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
⨯

The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

Ehm A. Andersson,
Marie N. Harder,
Kasper Pilgaard,
Charlotta Pisinger,
Alena Stančáková,
Johanna Kuusisto,
Niels Grarup,
Kristine Færch,
Pernille Poulsen,
Daniel R. Witte

Published: November 4, 2011
https://doi.org/10.1371/journal.pone.0027096

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