Deletion of Exon 20 of the Familial Dysautonomia Gene Ikbkap in Mice Causes Developmental Delay, Cardiovascular Defects, and Early Embryonic Lethality

Open Access

Peer-reviewed

Research Article

Paula Dietrich ,

Contributed equally to this work with: Paula Dietrich, Junming Yue

Affiliation Department of Physiology, College of Medicine, The University of Tennessee, Health Science Center, Memphis, Tennessee, United States of America
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Junming Yue ,

Contributed equally to this work with: Paula Dietrich, Junming Yue

Affiliation Department of Physiology, College of Medicine, The University of Tennessee, Health Science Center, Memphis, Tennessee, United States of America
⨯
Shuyu E.,

Affiliation Department of Physiology, College of Medicine, The University of Tennessee, Health Science Center, Memphis, Tennessee, United States of America
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Ioannis Dragatsis

* E-mail: idragatsis@uthsc.edu

Affiliation Department of Physiology, College of Medicine, The University of Tennessee, Health Science Center, Memphis, Tennessee, United States of America
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Embryos
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Genotyping
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Mouse models
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Histology
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Polymerase chain reaction
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SMAD signaling
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Gene expression
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Heterozygosity
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