Genetic Ablation of PLA2G6 in Mice Leads to Cerebellar Atrophy Characterized by Purkinje Cell Loss and Glial Cell Activation

Open Access

Peer-reviewed

Research Article

Zhengshan Zhao,

Affiliation Division of Experimental Diabetes and Aging, Department of Geriatrics and Palliative Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Jing Wang,

Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America
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Chunying Zhao,

Affiliation Division of Experimental Diabetes and Aging, Department of Geriatrics and Palliative Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Weina Bi,

Affiliation Division of Experimental Diabetes and Aging, Department of Geriatrics and Palliative Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Zhenyu Yue,

Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America
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Zhongmin Alex Ma

* E-mail: zhongmin.ma@mssm.edu

Affiliation Division of Experimental Diabetes and Aging, Department of Geriatrics and Palliative Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
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Atrophy
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Mouse models
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Purkinje cells
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Microglial cells
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Cerebellum
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Central nervous system
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Cytokines
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Granule cells
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