Interleukin-1 as an Injury Signal Mobilizes Retinyl Esters in Hepatic Stellate Cells through Down Regulation of Lecithin Retinol Acyltransferase

Yujiro Kida; Zanxian Xia; Sujun Zheng; Nicholas M. Mordwinkin; Stan G. Louie; Song Guo Zheng; Min Feng; Hongbo Shi; Zhongping Duan; Yuan-Ping Han

doi:10.1371/journal.pone.0026644

Loading metrics

Open Access

Peer-reviewed

Research Article

Interleukin-1 as an Injury Signal Mobilizes Retinyl Esters in Hepatic Stellate Cells through Down Regulation of Lecithin Retinol Acyltransferase

Yujiro Kida,

Current address: Division of Nephrology and Center for Lung Biology, Department of Medicine, University of Washington, Seattle, United States of America

Affiliation Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
⨯
Zanxian Xia,

Affiliation Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
⨯
Sujun Zheng,

Affiliation Beijing YouAn Hospital, Capital Medical University, Beijing, The People's Republic of China
⨯
Nicholas M. Mordwinkin,

Affiliation School of Pharmacy, University of Southern California, Los Angeles, California, United States of America
⨯
Stan G. Louie,

Affiliation School of Pharmacy, University of Southern California, Los Angeles, California, United States of America
⨯
Song Guo Zheng,

Affiliation Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
⨯
Min Feng,

Affiliation Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
⨯
Hongbo Shi,

Affiliation Beijing YouAn Hospital, Capital Medical University, Beijing, The People's Republic of China
⨯
Zhongping Duan ,

* E-mail: yhan@surgery.usc.edu (Y-PH); duan2517@163.com.cn (ZD)

Affiliation Beijing YouAn Hospital, Capital Medical University, Beijing, The People's Republic of China
⨯
Yuan-Ping Han

* E-mail: yhan@surgery.usc.edu (Y-PH); duan2517@163.com.cn (ZD)

Affiliations Beijing YouAn Hospital, Capital Medical University, Beijing, The People's Republic of China, Beijing Hepo Medical Research Institute, Beijing, The People's Republic of China, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
⨯

Interleukin-1 as an Injury Signal Mobilizes Retinyl Esters in Hepatic Stellate Cells through Down Regulation of Lecithin Retinol Acyltransferase

Yujiro Kida,
Zanxian Xia,
Sujun Zheng,
Nicholas M. Mordwinkin,
Stan G. Louie,
Song Guo Zheng,
Min Feng,
Hongbo Shi,
Zhongping Duan,
Yuan-Ping Han

Published: November 4, 2011
https://doi.org/10.1371/journal.pone.0026644

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Esters
Is the Subject Area "Esters" applicable to this article?

Thanks for your feedback.
Vitamin A
Is the Subject Area "Vitamin A" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Wound healing
Is the Subject Area "Wound healing" applicable to this article?

Thanks for your feedback.
Protein expression
Is the Subject Area "Protein expression" applicable to this article?

Thanks for your feedback.
Retinoic acid
Is the Subject Area "Retinoic acid" applicable to this article?

Thanks for your feedback.