Comparison of Therapeutic Effects between Pulsed and Continuous Wave 810-nm Wavelength Laser Irradiation for Traumatic Brain Injury in Mice

Takahiro Ando; Weijun Xuan; Tao Xu; Tianhong Dai; Sulbha K. Sharma; Gitika B. Kharkwal; Ying-Ying Huang; Qiuhe Wu; Michael J. Whalen; Shunichi Sato; Minoru Obara; Michael R. Hamblin

doi:10.1371/journal.pone.0026212

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Open Access

Peer-reviewed

Research Article

Comparison of Therapeutic Effects between Pulsed and Continuous Wave 810-nm Wavelength Laser Irradiation for Traumatic Brain Injury in Mice

Takahiro Ando,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Electronics and Electrical Engineering, Keio University, Yokohama, Japan
⨯
Weijun Xuan,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Otolaryngology, Traditional Chinese Medical University of Guangxi, Nanning, China
⨯
Tao Xu,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America, Laboratory of Anesthesiology, Shanghai Jiaotong University, Shanghai, China
⨯
Tianhong Dai,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Sulbha K. Sharma,

Affiliation Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Gitika B. Kharkwal,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ying-Ying Huang,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America, Aesthetic and Plastic Center, Guangxi Medical University, Nanning, China
⨯
Qiuhe Wu,

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Burns and Plastic Surgery, Shandong University, Jinan Central Hospital, Jinan, China
⨯
Michael J. Whalen,

Affiliation Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Shunichi Sato,

Affiliation Division of Biomedical Information Sciences, National Defense Medical College Research Institute, Tokorozawa, Japan
⨯
Minoru Obara,

Affiliation Department of Electronics and Electrical Engineering, Keio University, Yokohama, Japan
⨯
Michael R. Hamblin

* E-mail: hamblin@helix.mgh.harvard.edu

Affiliations Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Dermatology, Harvard Medical School, Boston, Massachusetts, United States of America, Harvard-MIT Division of Health Sciences and Technology, Harvard University, Cambridge, Massachusetts, United States of America
⨯

Comparison of Therapeutic Effects between Pulsed and Continuous Wave 810-nm Wavelength Laser Irradiation for Traumatic Brain Injury in Mice

Takahiro Ando,
Weijun Xuan,
Tao Xu,
Tianhong Dai,
Sulbha K. Sharma,
Gitika B. Kharkwal,
Ying-Ying Huang,
Qiuhe Wu,
Michael J. Whalen,
Shunichi Sato

Published: October 18, 2011
https://doi.org/10.1371/journal.pone.0026212

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