RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma

Qichao Huang; Biaoyang Lin; Hanqiang Liu; Xi Ma; Fan Mo; Wei Yu; Lisha Li; Hongwei Li; Tian Tian; Dong Wu; Feng Shen; Jinliang Xing; Zhi-Nan Chen

doi:10.1371/journal.pone.0026168

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Open Access

Peer-reviewed

Research Article

RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma

Qichao Huang ,

Contributed equally to this work with: Qichao Huang, Biaoyang Lin

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯
Biaoyang Lin ,

Contributed equally to this work with: Qichao Huang, Biaoyang Lin

Affiliations Systems Biology Division, Zhejiang–California International Nanosystems Institute (ZCNI), Zhejiang University, Hangzhou, China, Department of Urology, University of Washington, Seattle, Washington, United States of America
⨯
Hanqiang Liu,

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯
Xi Ma,

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯
Fan Mo,

Affiliation Systems Biology Division, Zhejiang–California International Nanosystems Institute (ZCNI), Zhejiang University, Hangzhou, China
⨯
Wei Yu,

Affiliation Systems Biology Division, Zhejiang–California International Nanosystems Institute (ZCNI), Zhejiang University, Hangzhou, China
⨯
Lisha Li,

Affiliation Systems Biology Division, Zhejiang–California International Nanosystems Institute (ZCNI), Zhejiang University, Hangzhou, China
⨯
Hongwei Li,

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯
Tian Tian,

Affiliation Institute of Life Science and Biotechnology, Beijing Jiaotong University, Beijing, People's Republic of China
⨯
Dong Wu,

Affiliation Department of Comprehensive Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China
⨯
Feng Shen,

Affiliation Department of Comprehensive Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China
⨯
Jinliang Xing ,

* E-mail: xingjinliang@163.com (JX); zhinanchen@fmmu.edu.cn (Z-NC)

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯
Zhi-Nan Chen

* E-mail: xingjinliang@163.com (JX); zhinanchen@fmmu.edu.cn (Z-NC)

Affiliation State Key Laboratory of Cancer Biology, Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an, China
⨯

RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma

Qichao Huang,
Biaoyang Lin,
Hanqiang Liu,
Xi Ma,
Fan Mo,
Wei Yu,
Lisha Li,
Hongwei Li,
Tian Tian,
Dong Wu

Published: October 17, 2011
https://doi.org/10.1371/journal.pone.0026168

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Gene expression
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Hepatocellular carcinoma
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RNA sequencing
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Exon mapping
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Cancers and neoplasms
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Transcriptome analysis
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Sequence alignment
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Gene sequencing
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