TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes

Marije Oosting; Hadewych ter Hofstede; Patrick Sturm; Gosse J. Adema; Bart-Jan Kullberg; Jos W. M. van der Meer; Mihai G. Netea; Leo A. B. Joosten

doi:10.1371/journal.pone.0025998

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Open Access

Peer-reviewed

Research Article

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes

Marije Oosting,

Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute of Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Hadewych ter Hofstede,

Affiliation Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Patrick Sturm,

Affiliation Department of Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Gosse J. Adema,

Affiliation Department of Tumor Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Bart-Jan Kullberg,

Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute of Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Jos W. M. van der Meer,

Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute of Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Mihai G. Netea,

Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute of Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Leo A. B. Joosten

* E-mail: l.joosten@aig.umcn.nl

Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute of Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes

Marije Oosting,
Hadewych ter Hofstede,
Patrick Sturm,
Gosse J. Adema,
Bart-Jan Kullberg,
Jos W. M. van der Meer,
Mihai G. Netea,
Leo A. B. Joosten

Published: October 5, 2011
https://doi.org/10.1371/journal.pone.0025998

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