In Vivo SPECT Reporter Gene Imaging of Regulatory T Cells

Ehsan Sharif-Paghaleh; Kavitha Sunassee; Richard Tavaré; Kulachelvy Ratnasothy; Alexander Koers; Niwa Ali; Rowa Alhabbab; Philip J. Blower; Robert I. Lechler; Lesley A. Smyth; Gregory E. Mullen; Giovanna Lombardi

doi:10.1371/journal.pone.0025857

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Open Access

Peer-reviewed

Research Article

In Vivo SPECT Reporter Gene Imaging of Regulatory T Cells

Ehsan Sharif-Paghaleh,

Affiliations Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom, Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Kavitha Sunassee,

Affiliation Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Richard Tavaré,

Affiliation Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Kulachelvy Ratnasothy,

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯
Alexander Koers,

Affiliation Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Niwa Ali,

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯
Rowa Alhabbab,

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯
Philip J. Blower,

Affiliation Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Robert I. Lechler,

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯
Lesley A. Smyth ,

Contributed equally to this work with: Lesley A. Smyth, Gregory E. Mullen, Giovanna Lombardi

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯
Gregory E. Mullen ,

Contributed equally to this work with: Lesley A. Smyth, Gregory E. Mullen, Giovanna Lombardi

* E-mail: giovanna.lombardi@kcl.ac.uk (GL); greg.mullen@kcl.ac.uk (GEM)

Affiliations Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom, Division of Imaging Sciences, King's College London, St Thomas Hospital, London, United Kingdom
⨯
Giovanna Lombardi

Contributed equally to this work with: Lesley A. Smyth, Gregory E. Mullen, Giovanna Lombardi

* E-mail: giovanna.lombardi@kcl.ac.uk (GL); greg.mullen@kcl.ac.uk (GEM)

Affiliation Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom
⨯

In Vivo SPECT Reporter Gene Imaging of Regulatory T Cells

Ehsan Sharif-Paghaleh,
Kavitha Sunassee,
Richard Tavaré,
Kulachelvy Ratnasothy,
Alexander Koers,
Niwa Ali,
Rowa Alhabbab,
Philip J. Blower,
Robert I. Lechler,
Lesley A. Smyth

Published: October 17, 2011
https://doi.org/10.1371/journal.pone.0025857

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Regulatory T cells
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Radiolabeling
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In vivo imaging
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Spleen
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Imaging techniques
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T cells
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Flow cytometry
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Single photon emission computed tomography
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