Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria

Ally Olotu; Philippe Moris; Jedidah Mwacharo; Johan Vekemans; Domtila Kimani; Michel Janssens; Oscar Kai; Erik Jongert; Marc Lievens; Amanda Leach; Tonya Villafana; Barbara Savarese; Kevin Marsh; Joe Cohen; Philip Bejon

doi:10.1371/journal.pone.0025786

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Peer-reviewed

Research Article

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01_E and Protection against P falciparum Clinical Malaria

Ally Olotu,

Affiliation Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya
⨯
Philippe Moris,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Jedidah Mwacharo,

Affiliation Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya
⨯
Johan Vekemans,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Domtila Kimani,

Affiliation Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya
⨯
Michel Janssens,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Oscar Kai,

Affiliation Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya
⨯
Erik Jongert,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Marc Lievens,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Amanda Leach,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Tonya Villafana,

Affiliations PATH Malaria Vaccine Initiative (MVI), Bethesda, Maryland, United States of America, MedImmune, LLC, Gaithersburg, Maryland, United States of America
⨯
Barbara Savarese,

Affiliation PATH Malaria Vaccine Initiative (MVI), Bethesda, Maryland, United States of America
⨯
Kevin Marsh,

Affiliations Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya, Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Joe Cohen,

Affiliation GlaxoSmithKline Biologicals, Rixensart, Belgium
⨯
Philip Bejon

* E-mail: pbejon@kilifi.kemri-wellcome.org

Affiliations Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi, Kenya, Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01_E and Protection against P falciparum Clinical Malaria

Ally Olotu,
Philippe Moris,
Jedidah Mwacharo,
Johan Vekemans,
Domtila Kimani,
Michel Janssens,
Oscar Kai,
Erik Jongert,
Marc Lievens,
Amanda Leach

Published: October 6, 2011
https://doi.org/10.1371/journal.pone.0025786

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