A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

Hamid Moha ou Maati; Rémi Peyronnet; Christelle Devader; Julie Veyssiere; Fabien Labbal; Carine Gandin; Jean Mazella; Catherine Heurteaux; Marc Borsotto

doi:10.1371/journal.pone.0025602

Loading metrics

Open Access

Peer-reviewed

Research Article

A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

Hamid Moha ou Maati,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Rémi Peyronnet,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Christelle Devader,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Julie Veyssiere,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Fabien Labbal,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Carine Gandin,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Jean Mazella,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Catherine Heurteaux,

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯
Marc Borsotto

* E-mail: borsotto@ipmc.cnrs.fr

Affiliation Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, Valbonne, France
⨯

A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

Hamid Moha ou Maati,
Rémi Peyronnet,
Christelle Devader,
Julie Veyssiere,
Fabien Labbal,
Carine Gandin,
Jean Mazella,
Catherine Heurteaux,
Marc Borsotto

Published: October 14, 2011
https://doi.org/10.1371/journal.pone.0025602

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Potassium channels
Is the Subject Area "Potassium channels" applicable to this article?

Thanks for your feedback.
Ischemia
Is the Subject Area "Ischemia" applicable to this article?

Thanks for your feedback.
HEK 293 cells
Is the Subject Area "HEK 293 cells" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Depression
Is the Subject Area "Depression" applicable to this article?

Thanks for your feedback.
Patch clamp techniques
Is the Subject Area "Patch clamp techniques" applicable to this article?

Thanks for your feedback.
Drug screening
Is the Subject Area "Drug screening" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.