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Open Access

Peer-reviewed

Research Article

Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

Lo-Kong Chan,

Affiliations Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
⨯
Frankie Chi Fat Ko,

Affiliations Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
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Karen Man-Fong Sze,

Affiliations Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong
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Irene Oi-Lin Ng ,

* E-mail: judyyam@pathology.hku.hk (JWPY); iolng@hku.hk (IO-LN)

Affiliations Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
⨯
Judy Wai Ping Yam

* E-mail: judyyam@pathology.hku.hk (JWPY); iolng@hku.hk (IO-LN)

Affiliations Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
⨯

Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

Lo-Kong Chan,
Frankie Chi Fat Ko,
Karen Man-Fong Sze,
Irene Oi-Lin Ng,
Judy Wai Ping Yam

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Published: September 26, 2011
https://doi.org/10.1371/journal.pone.0025547

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Transfection
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Focal adhesions
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Hepatocellular carcinoma
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Cancers and neoplasms
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Cytoplasm
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Nuclear staining
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Immunohistochemistry techniques
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Subcellular localization
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