α,β-D-Constrained Nucleic Acids Are Strong Terminators of Thermostable DNA Polymerases in Polymerase Chain Reaction

Olivier Martínez; Vincent Ecochard; Sabrina Mahéo; Grégori Gross; Pierre Bodin; Justin Teissié; Jean-Marc Escudier; Laurent Paquereau

doi:10.1371/journal.pone.0025510

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Peer-reviewed

Research Article

α,β-D-Constrained Nucleic Acids Are Strong Terminators of Thermostable DNA Polymerases in Polymerase Chain Reaction

Olivier Martínez ,

Contributed equally to this work with: Olivier Martínez, Vincent Ecochard

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Vincent Ecochard ,

Contributed equally to this work with: Olivier Martínez, Vincent Ecochard

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Sabrina Mahéo,

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Grégori Gross,

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Pierre Bodin,

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Justin Teissié,

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯
Jean-Marc Escudier,

Affiliation Laboratoire de Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique, Unité Mixte de Recherche 5068, Centre National de la Recherche Scientifique, Toulouse , France
⨯
Laurent Paquereau

* E-mail: Laurent.Paquereau@ipbs.fr

Affiliations Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, Centre National de la Recherche Scientifique, Toulouse, France, Université Paul Sabatier Toulouse III, Faculté des Sciences et d'Ingénierie, Toulouse, France
⨯

α,β-D-Constrained Nucleic Acids Are Strong Terminators of Thermostable DNA Polymerases in Polymerase Chain Reaction

Olivier Martínez,
Vincent Ecochard,
Sabrina Mahéo,
Grégori Gross,
Pierre Bodin,
Justin Teissié,
Jean-Marc Escudier,
Laurent Paquereau

Published: October 3, 2011
https://doi.org/10.1371/journal.pone.0025510

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