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Open Access

Peer-reviewed

Research Article

Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

Qilong Wang,

Affiliation Section of Molecular Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Miao Zhang,

Affiliation Section of Molecular Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Bin Liang,

Affiliation Section of Molecular Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Najeeb Shirwany,

Affiliation Section of Molecular Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Yi Zhu,

Affiliation Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China
⨯
Ming-Hui Zou

* E-mail: ming-hui-zou@ouhsc.edu

Affiliations Section of Molecular Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯

Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

Qilong Wang,
Miao Zhang,
Bin Liang,
Najeeb Shirwany,
Yi Zhu,
Ming-Hui Zou

x

Published: September 27, 2011
https://doi.org/10.1371/journal.pone.0025436

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Atherosclerosis
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Small interfering RNA
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Mitochondria
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Aorta
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Endothelial cells
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Transfection
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Cholesterol
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