Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction

Xian-Liang Tang; Santosh K. Sanganalmath; Hiroshi Sato; Qiuli Bi; Greg Hunt; Robert J. Vincent; Yong Peng; Gregg Shirk; Buddhadeb Dawn; Roberto Bolli

doi:10.1371/journal.pone.0025320

Loading metrics

Open Access

Peer-reviewed

Research Article

Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction

Xian-Liang Tang ,

Contributed equally to this work with: Xian-Liang Tang, Santosh K. Sanganalmath

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Santosh K. Sanganalmath ,

Contributed equally to this work with: Xian-Liang Tang, Santosh K. Sanganalmath

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Hiroshi Sato,

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Qiuli Bi,

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Greg Hunt,

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Robert J. Vincent,

Affiliation Cardiovascular Research Institute, Kansas University Medical Center, Kansas City, Kansas, United States of America
⨯
Yong Peng,

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Gregg Shirk,

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Buddhadeb Dawn,

Affiliation Cardiovascular Research Institute, Kansas University Medical Center, Kansas City, Kansas, United States of America
⨯
Roberto Bolli

* E-mail: rbolli@louisville.edu

Affiliation Division of Cardiovascular Medicine and Institute of Molecular Cardiology, University of Louisville, Louisville, Kentucky, United States of America
⨯

Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction

Xian-Liang Tang,
Santosh K. Sanganalmath,
Hiroshi Sato,
Qiuli Bi,
Greg Hunt,
Robert J. Vincent,
Yong Peng,
Gregg Shirk,
Buddhadeb Dawn,
Roberto Bolli

Published: September 28, 2011
https://doi.org/10.1371/journal.pone.0025320

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Myocardial infarction
Is the Subject Area "Myocardial infarction" applicable to this article?

Thanks for your feedback.
Statins
Is the Subject Area "Statins" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Cardiomyocytes
Is the Subject Area "Cardiomyocytes" applicable to this article?

Thanks for your feedback.
Fibrosis
Is the Subject Area "Fibrosis" applicable to this article?

Thanks for your feedback.
Collagens
Is the Subject Area "Collagens" applicable to this article?

Thanks for your feedback.
Hemodynamics
Is the Subject Area "Hemodynamics" applicable to this article?

Thanks for your feedback.