Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model

Open Access

Peer-reviewed

Research Article

Gene Ananiev,

Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Emily Cunningham Williams,

Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Genetics Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Hongda Li,

Affiliations Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Genetics Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Qiang Chang

* E-mail: qchang@waisman.wisc.edu

Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Genetics Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Genetics and Neurology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Neuronal differentiation
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Induced pluripotent stem cells
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Fibroblasts
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DNA methylation
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Polymerase chain reaction
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Mouse models
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Deletion mutation
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X chromosome inactivation
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