A Toll-Like Receptor 2 Pathway Regulates the Ppargc1a/b Metabolic Co-Activators in Mice with Staphylococcal aureus Sepsis

Open Access

Peer-reviewed

Research Article

Timothy E. Sweeney,

Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Hagir B. Suliman,

Affiliation Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, United States of America
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John W. Hollingsworth,

Affiliations Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Karen E. Welty-Wolf,

Affiliation Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Claude A. Piantadosi

* E-mail: piant001@mc.duke.edu

Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

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Staphylococcus aureus
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Sepsis
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Immune receptor signaling
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Transcription factors
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Mitochondria
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Mouse models
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PPAR signaling
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Toll-like receptors
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