Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

• Nicole Speed ,

  Contributed equally to this work with: Nicole Speed, Christine Saunders

  Affiliation Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Christine Saunders ,

  Contributed equally to this work with: Nicole Speed, Christine Saunders

  Affiliation Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Adeola R. Davis,

  Affiliation Department of Molecular Physiology and Biophysics, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• W. Anthony Owens,

  Affiliation Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Heinrich J. G. Matthies,

  Affiliation Department of Molecular Physiology and Biophysics, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Sanaz Saadat,

  Affiliation Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America

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• Jack P. Kennedy,

  Affiliation Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Roxanne A. Vaughan,

  Affiliation Department of Biochemistry and Molecular Biology, School of Medicine and Health Science, University of North Dakota, Grand Forks, North Dakota, United States of America

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• Rachael L. Neve,

  Affiliation Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Craig W. Lindsley,

  Affiliation Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Scott J. Russo,

  Affiliation Department of Neuroscience, Mount Sinai Medical Center, New York, New York, United States of America

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• Lynette C. Daws ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Kevin D. Niswender1 ,

  ¶These authors also contributed equally to this work.

  Affiliations Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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• Aurelio Galli

  * E-mail: aurelio.galli@vanderbilt.edu

  ¶These authors also contributed equally to this work.

  Affiliations Department of Molecular Physiology and Biophysics, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America, Center for Molecular Neuroscience, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

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