Multiple Statistical Analysis Techniques Corroborate Intratumor Heterogeneity in Imaging Mass Spectrometry Datasets of Myxofibrosarcoma

Open Access

Peer-reviewed

Research Article

Emrys A. Jones,

Affiliation Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Alexandra van Remoortere,

Affiliation Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
⨯
René J. M. van Zeijl,

Affiliation Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Pancras C. W. Hogendoorn,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Judith V. M. G. Bovée,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
André M. Deelder,

Affiliation Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Liam A. McDonnell

* E-mail: l.a.mcdonnell@lumc.nl

Affiliation Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
⨯

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Imaging techniques
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Histology
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Principal component analysis
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Algorithms
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Data reduction
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Mass spectra
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Statistical data
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k means clustering
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