The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

Yong He; Arlene M. Correa; Maria Gabriela Raso; Wayne L. Hofstetter; Bingliang Fang; Carmen Behrens; Jack A. Roth; Yihong Zhou; Liping Yu; Ignacio I. Wistuba; Stephen G. Swisher; Apar Pataer

doi:10.1371/journal.pone.0024855

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Open Access

Peer-reviewed

Research Article

The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

Yong He,

Affiliations Department of Thoracic Surgery, Daping Hospital, Third Military Medical University, Chongqing, China, Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Arlene M. Correa,

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Maria Gabriela Raso,

Affiliation Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Wayne L. Hofstetter,

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Bingliang Fang,

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
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Carmen Behrens,

Affiliation Department of Thoracic Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
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Jack A. Roth,

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yihong Zhou,

Affiliation Department of Neurological Surgery and Biological Chemistry, University of California Irvine, Irvine, California, United States of America
⨯
Liping Yu,

Affiliation Ziren Research LLC, Irvine, California, United States of America
⨯
Ignacio I. Wistuba,

Affiliations Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Thoracic Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Stephen G. Swisher,

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Apar Pataer

* E-mail: apataer@mdanderson.org

Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

Yong He,
Arlene M. Correa,
Maria Gabriela Raso,
Wayne L. Hofstetter,
Bingliang Fang,
Carmen Behrens,
Jack A. Roth,
Yihong Zhou,
Liping Yu,
Ignacio I. Wistuba

Published: November 10, 2011
https://doi.org/10.1371/journal.pone.0024855

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Non-small cell lung cancer
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Protein expression
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Phosphorylation
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Cancers and neoplasms
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Head and neck cancers
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Prognosis
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Apoptosis
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Breast cancer
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