Genome-Wide Linkage Scan of a Pedigree with Familial Hypercholesterolemia Suggests Susceptibility Loci on Chromosomes 3q25-26 and 21q22

Xu Wang; Xin Li; Yong-Biao Zhang; Feng Zhang; Liyuan Sun; Jie Lin; Duen-Mei Wang; Lu-Ya Wang

doi:10.1371/journal.pone.0024838

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Research Article

Genome-Wide Linkage Scan of a Pedigree with Familial Hypercholesterolemia Suggests Susceptibility Loci on Chromosomes 3q25-26 and 21q22

Xu Wang ,

Contributed equally to this work with: Xu Wang, Xin Li

Affiliation The Key Laboratory of Remodeling-related Cardiovascular Diseases, Capital Medical University, Ministry of Education, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, People's Republic of China
⨯
Xin Li ,

Contributed equally to this work with: Xu Wang, Xin Li

Affiliation CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Yong-Biao Zhang,

Affiliation CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Feng Zhang,

Affiliation CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Liyuan Sun,

Affiliation The Key Laboratory of Remodeling-related Cardiovascular Diseases, Capital Medical University, Ministry of Education, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, People's Republic of China
⨯
Jie Lin,

Affiliation The Key Laboratory of Remodeling-related Cardiovascular Diseases, Capital Medical University, Ministry of Education, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, People's Republic of China
⨯
Duen-Mei Wang,

Affiliation CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Lu-Ya Wang

* E-mail: wangluya@126.com (L-YW)

Affiliation The Key Laboratory of Remodeling-related Cardiovascular Diseases, Capital Medical University, Ministry of Education, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing, People's Republic of China
⨯

Genome-Wide Linkage Scan of a Pedigree with Familial Hypercholesterolemia Suggests Susceptibility Loci on Chromosomes 3q25-26 and 21q22

Xu Wang,
Xin Li,
Yong-Biao Zhang,
Feng Zhang,
Liyuan Sun,
Jie Lin,
Duen-Mei Wang,
Lu-Ya Wang

Published: October 14, 2011
https://doi.org/10.1371/journal.pone.0024838

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Genetic loci
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Familial hypercholesterolemia
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Linkage analysis
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Single nucleotide polymorphisms
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