Origination of New Immunological Functions in the Costimulatory Molecule B7-H3: The Role of Exon Duplication in Evolution of the Immune System

• Jing Sun ,

  Contributed equally to this work with: Jing Sun, Fengqing Fu

  Affiliation Suzhou Health Technology College, Suzhou, China

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• Fengqing Fu ,

  Contributed equally to this work with: Jing Sun, Fengqing Fu

  Affiliations Institute of Medical Biotechnology, Soochow University, Suzhou, China, Clinical Immunology Laboratory, First Affiliated Hospital, Suzhou, China

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• Wenchao Gu,

  Affiliations Institute of Medical Biotechnology, Soochow University, Suzhou, China, Stem Cell Research Laboratory of Jiangsu Province, Suzhou, China

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• Ruhong Yan,

  Affiliations Institute of Medical Biotechnology, Soochow University, Suzhou, China, Clinical Immunology Laboratory, First Affiliated Hospital, Suzhou, China

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• Guangbo Zhang,

  Affiliations Stem Cell Research Laboratory of Jiangsu Province, Suzhou, China, Clinical Immunology Laboratory, First Affiliated Hospital, Suzhou, China

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• Zhiyong Shen,

  Affiliation Institute of Medical Biotechnology, Soochow University, Suzhou, China

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• Yinghui Zhou,

  Affiliation Institute of Medical Biotechnology, Soochow University, Suzhou, China

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• Han Wang,

  Affiliation Laboratory of Developmental Genetics and Genomics Medical College, Soochow University, Suzhou, China

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• Bairong Shen ,

  * E-mail: xueguangzh@yahoo.com.cn (XZ); bairong.shen@suda.edu.cn (BS)

  Affiliation Center for Systems Biology, Soochow University, Suzhou, China

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• Xueguang Zhang

  * E-mail: xueguangzh@yahoo.com.cn (XZ); bairong.shen@suda.edu.cn (BS)

  Affiliations Institute of Medical Biotechnology, Soochow University, Suzhou, China, Stem Cell Research Laboratory of Jiangsu Province, Suzhou, China, Clinical Immunology Laboratory, First Affiliated Hospital, Suzhou, China

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