High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells

Sandeep Dayal; Jakub Nedbal; Philip Hobson; Alison M. Cooper; Hannah J. Gould; Martin Gellert; Gary Felsenfeld; David J. Fear

doi:10.1371/journal.pone.0024571

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Peer-reviewed

Research Article

High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells

Sandeep Dayal,

Affiliation Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jakub Nedbal,

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom, Randall Division of Cell and Molecular Biophysics, King's College London, London, United Kingdom
⨯
Philip Hobson,

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom, Randall Division of Cell and Molecular Biophysics, King's College London, London, United Kingdom
⨯
Alison M. Cooper,

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom, Randall Division of Cell and Molecular Biophysics, King's College London, London, United Kingdom
⨯
Hannah J. Gould,

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom, Randall Division of Cell and Molecular Biophysics, King's College London, London, United Kingdom
⨯
Martin Gellert,

Affiliation Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Gary Felsenfeld ,

* E-mail: david.fear@kcl.ac.uk (DJF); garyf@intra.niddk.nih.gov (GF)

Affiliation Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
David J. Fear

* E-mail: david.fear@kcl.ac.uk (DJF); garyf@intra.niddk.nih.gov (GF)

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom
⨯

High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells

Sandeep Dayal,
Jakub Nedbal,
Philip Hobson,
Alison M. Cooper,
Hannah J. Gould,
Martin Gellert,
Gary Felsenfeld,
David J. Fear

Published: September 20, 2011
https://doi.org/10.1371/journal.pone.0024571

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B cells
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Chromatin
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DNA methylation
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Histones
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Histone modification
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Acetylation
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DNA transcription
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Nucleosomes
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