Direct Effects of HIV-1 Tat on Excitability and Survival of Primary Dorsal Root Ganglion Neurons: Possible Contribution to HIV-1-Associated Pain

Xianxun Chi; Tohti Amet; Daniel Byrd; Kuei-Hua Chang; Kavita Shah; Ningjie Hu; Ayslinn Grantham; Sishun Hu; Jianhong Duan; Feng Tao; Grant Nicol; Qigui Yu

doi:10.1371/journal.pone.0024412

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Open Access

Peer-reviewed

Research Article

Direct Effects of HIV-1 Tat on Excitability and Survival of Primary Dorsal Root Ganglion Neurons: Possible Contribution to HIV-1-Associated Pain

Xianxun Chi ,

Contributed equally to this work with: Xianxun Chi, Tohti Amet

Affiliation Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Tohti Amet ,

Contributed equally to this work with: Xianxun Chi, Tohti Amet

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Daniel Byrd,

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Kuei-Hua Chang,

Affiliation Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, United States of America
⨯
Kavita Shah,

Affiliation Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, United States of America
⨯
Ningjie Hu,

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Ayslinn Grantham,

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Sishun Hu,

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Jianhong Duan,

Affiliation Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Feng Tao,

Affiliation Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Grant Nicol,

Affiliation Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Qigui Yu

* E-mail: andyu@iupui.edu

Affiliation Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯

Direct Effects of HIV-1 Tat on Excitability and Survival of Primary Dorsal Root Ganglion Neurons: Possible Contribution to HIV-1-Associated Pain

Xianxun Chi,
Tohti Amet,
Daniel Byrd,
Kuei-Hua Chang,
Kavita Shah,
Ningjie Hu,
Ayslinn Grantham,
Sishun Hu,
Jianhong Duan,
Feng Tao

Published: September 2, 2011
https://doi.org/10.1371/journal.pone.0024412

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