Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids

Els Robanus-Maandag; Cathy Bosch; Saeid Amini-Nik; Jeroen Knijnenburg; Karoly Szuhai; Pascale Cervera; Raymond Poon; Diana Eccles; Paolo Radice; Marco Giovannini; Benjamin A. Alman; Sabine Tejpar; Peter Devilee; Riccardo Fodde

doi:10.1371/journal.pone.0024354

Loading metrics

Open Access

Peer-reviewed

Research Article

Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids

Els Robanus-Maandag ,

* E-mail: e.c.robanus@lumc.nl

Affiliation Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
⨯
Cathy Bosch,

Affiliation Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
⨯
Saeid Amini-Nik,

Affiliations Center for Human Genetics, University of Leuven, Leuven, Belgium, Division of Orthopaedic Surgery and Department of Surgery, University of Toronto and the Hospital for Sick Children, Toronto, Canada
⨯
Jeroen Knijnenburg,

Affiliation Department of Molecular Cellular Biology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Karoly Szuhai,

Affiliation Department of Molecular Cellular Biology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Pascale Cervera,

Affiliation INSERM U674, Fondation Jean Dausset-CEPH, Paris, France
⨯
Raymond Poon,

Affiliation Division of Orthopaedic Surgery and Department of Surgery, University of Toronto and the Hospital for Sick Children, Toronto, Canada
⨯
Diana Eccles,

Affiliation Wessex Clinical Genetics Service, Southampton University Hospitals Trust, Southampton, United Kingdom
⨯
Paolo Radice,

Affiliation Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Marco Giovannini,

Affiliation INSERM U674, Fondation Jean Dausset-CEPH, Paris, France
⨯
Benjamin A. Alman,

Affiliation Division of Orthopaedic Surgery and Department of Surgery, University of Toronto and the Hospital for Sick Children, Toronto, Canada
⨯
Sabine Tejpar,

Affiliation Center for Human Genetics, University of Leuven, Leuven, Belgium
⨯
Peter Devilee,

Affiliation Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
⨯
Riccardo Fodde

Affiliation Department of Pathology, Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, The Netherlands
⨯

Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids

Els Robanus-Maandag,
Cathy Bosch,
Saeid Amini-Nik,
Jeroen Knijnenburg,
Karoly Szuhai,
Pascale Cervera,
Raymond Poon,
Diana Eccles,
Paolo Radice,
Marco Giovannini

Published: September 9, 2011
https://doi.org/10.1371/journal.pone.0024354

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Antigen-presenting cells
Is the Subject Area "Antigen-presenting cells" applicable to this article?

Thanks for your feedback.
Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Array CGH
Is the Subject Area "Array CGH" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Tumor suppressor genes
Is the Subject Area "Tumor suppressor genes" applicable to this article?

Thanks for your feedback.
Gastric cancer
Is the Subject Area "Gastric cancer" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.