Unpolarized Release of Vaccinia Virus and HIV Antigen by Colchicine Treatment Enhances Intranasal HIV Antigen Expression and Mucosal Humoral Responses

Yan Zhang; Jingyi Yang; Rong Bao; Yaoqing Chen; Dihan Zhou; Benxia He; Maohua Zhong; Yaoming Li; Fang Liu; Qiaoli Li; Yi Yang; Chen Han; Ying Sun; Yuan Cao; Huimin Yan

doi:10.1371/journal.pone.0024296

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Open Access

Peer-reviewed

Research Article

Unpolarized Release of Vaccinia Virus and HIV Antigen by Colchicine Treatment Enhances Intranasal HIV Antigen Expression and Mucosal Humoral Responses

Yan Zhang,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Jingyi Yang,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Rong Bao,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Yaoqing Chen,

Affiliation The State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Dihan Zhou,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Benxia He,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Maohua Zhong,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Yaoming Li,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Fang Liu,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Qiaoli Li,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Yi Yang,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Chen Han,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Ying Sun,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Yuan Cao,

Affiliation Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
⨯
Huimin Yan

* E-mail: hmyan@wh.iov.cn

Affiliations Mucosal Immunity Research Group, the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, The State Key Laboratory of Virology and Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China
⨯

Unpolarized Release of Vaccinia Virus and HIV Antigen by Colchicine Treatment Enhances Intranasal HIV Antigen Expression and Mucosal Humoral Responses

Yan Zhang,
Jingyi Yang,
Rong Bao,
Yaoqing Chen,
Dihan Zhou,
Benxia He,
Maohua Zhong,
Yaoming Li,
Fang Liu,
Qiaoli Li

Published: September 15, 2011
https://doi.org/10.1371/journal.pone.0024296

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