The Combination of BH3-Mimetic ABT-737 with the Alkylating Agent Temozolomide Induces Strong Synergistic Killing of Melanoma Cells Independent of p53

Open Access

Peer-reviewed

Research Article

Steven N. Reuland,

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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Nathaniel B. Goldstein,

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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Katie A. Partyka,

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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David A. Cooper,

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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Mayumi Fujita,

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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David A. Norris ,

Contributed equally to this work with: David A. Norris, Yiqun G. Shellman

Affiliations University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America, Department of Veterans Affairs Medical Center, Dermatology Section, Denver, Colorado, United States of America
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Yiqun G. Shellman

Contributed equally to this work with: David A. Norris, Yiqun G. Shellman

* E-mail: yiqun.shellman@ucdenver.edu

Affiliation University of Colorado Denver, School of Medicine, Department of Dermatology, Aurora, Colorado, United States of America
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Apoptosis
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Cancer treatment
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Melanoma cells
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Drug therapy
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Melanoma
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Cell death
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Immunoblotting
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Malignant tumors
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