Novel Biomarkers Distinguishing Active Tuberculosis from Latent Infection Identified by Gene Expression Profile of Peripheral Blood Mononuclear Cells

Chanyi Lu; Jing Wu; Honghai Wang; Sen Wang; Ni Diao; Feifei Wang; Yan Gao; Jiazhen Chen; Lingyun Shao; Xinhua Weng; Ying Zhang; Wenhong Zhang

doi:10.1371/journal.pone.0024290

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Open Access

Peer-reviewed

Research Article

Novel Biomarkers Distinguishing Active Tuberculosis from Latent Infection Identified by Gene Expression Profile of Peripheral Blood Mononuclear Cells

Chanyi Lu,

Affiliations Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China, State Key Laboratory of Genetic Engineering(SKLGE), Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
⨯
Jing Wu,

Affiliations Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China, State Key Laboratory of Genetic Engineering(SKLGE), Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
⨯
Honghai Wang,

Affiliation State Key Laboratory of Genetic Engineering(SKLGE), Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
⨯
Sen Wang,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Ni Diao,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Feifei Wang,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Yan Gao,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Jiazhen Chen,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Lingyun Shao,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Xinhua Weng,

Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
⨯
Ying Zhang ,

* E-mail: zhangwenhong@fudan.edu.cn (WZ); pharmlife2002@yahoo.com (YZ)

Affiliations Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Wenhong Zhang

* E-mail: zhangwenhong@fudan.edu.cn (WZ); pharmlife2002@yahoo.com (YZ)

Affiliations Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China, Institutes of Biomedical Sciences, Fudan University, Shanghai, China
⨯

Novel Biomarkers Distinguishing Active Tuberculosis from Latent Infection Identified by Gene Expression Profile of Peripheral Blood Mononuclear Cells

Chanyi Lu,
Jing Wu,
Honghai Wang,
Sen Wang,
Ni Diao,
Feifei Wang,
Yan Gao,
Jiazhen Chen,
Lingyun Shao,
Xinhua Weng

Published: August 31, 2011
https://doi.org/10.1371/journal.pone.0024290

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Gene expression
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Mycobacterium tuberculosis
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