Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

Yuki Sakazaki; Tomoaki Hoshino; Satoko Takei; Masanori Sawada; Hanako Oda; Shin-ichi Takenaka; Haruki Imaoka; Kazuko Matsunaga; Toshio Ota; Yuzuru Abe; Ichiro Miki; Kiminori Fujimoto; Tomotaka Kawayama; Seiya Kato; Hisamichi Aizawa

doi:10.1371/journal.pone.0024177

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Peer-reviewed

Research Article

Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

Yuki Sakazaki,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Tomoaki Hoshino ,

* E-mail: hoshino@med.kurume-u.ac.jp

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Satoko Takei,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Masanori Sawada,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Hanako Oda,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Shin-ichi Takenaka,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Haruki Imaoka,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Kazuko Matsunaga,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Toshio Ota,

Affiliation Drug Discovery Research Laboratories, Kyowa Hakko Kirin Co., Ltd., Shizuoka, Japan
⨯
Yuzuru Abe,

Affiliation Drug Discovery Research Laboratories, Kyowa Hakko Kirin Co., Ltd., Shizuoka, Japan
⨯
Ichiro Miki,

Affiliation Drug Discovery Research Laboratories, Kyowa Hakko Kirin Co., Ltd., Shizuoka, Japan
⨯
Kiminori Fujimoto,

Affiliation Department of Radiology and Center for Diagnostic Imaging, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Tomotaka Kawayama,

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯
Seiya Kato,

Affiliation Division of Pathology and Cell Biology, Graduate School and Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan
⨯
Hisamichi Aizawa †

† Deceased.

Affiliation Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
⨯

Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

Yuki Sakazaki,
Tomoaki Hoshino,
Satoko Takei,
Masanori Sawada,
Hanako Oda,
Shin-ichi Takenaka,
Haruki Imaoka,
Kazuko Matsunaga,
Toshio Ota,
Yuzuru Abe

Published: September 7, 2011
https://doi.org/10.1371/journal.pone.0024177

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