Cetuximab Augments Cytotoxicity with Poly (ADP-Ribose) Polymerase Inhibition in Head and Neck Cancer

Somaira Nowsheen; James A. Bonner; Albert F. LoBuglio; Hoa Trummell; Alexander C. Whitley; Michael C. Dobelbower; Eddy S. Yang

doi:10.1371/journal.pone.0024148

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Open Access

Peer-reviewed

Research Article

Cetuximab Augments Cytotoxicity with Poly (ADP-Ribose) Polymerase Inhibition in Head and Neck Cancer

Somaira Nowsheen,

Affiliation Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
James A. Bonner,

Affiliation Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
Albert F. LoBuglio,

Affiliation Department of Hematology/Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
Hoa Trummell,

Affiliation Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
Alexander C. Whitley,

Affiliation Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
Michael C. Dobelbower,

Affiliation Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America
⨯
Eddy S. Yang

* E-mail: eyang@uab.edu

Affiliations Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America, Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯

Cetuximab Augments Cytotoxicity with Poly (ADP-Ribose) Polymerase Inhibition in Head and Neck Cancer

Somaira Nowsheen,
James A. Bonner,
Albert F. LoBuglio,
Hoa Trummell,
Alexander C. Whitley,
Michael C. Dobelbower,
Eddy S. Yang

Published: August 30, 2011
https://doi.org/10.1371/journal.pone.0024148

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DNA repair
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Head and neck cancers
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Lung and intrathoracic tumors
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