P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

Suffwan Eltom; Christopher S. Stevenson; Joseph Rastrick; Nicole Dale; Kristof Raemdonck; Sissie Wong; Matthew C. Catley; Maria G. Belvisi; Mark A. Birrell

doi:10.1371/journal.pone.0024097

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Peer-reviewed

Research Article

P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

Suffwan Eltom,

Affiliations Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Centre for Integrative Mammalian Physiology and Pharmacology, Imperial College London, London, United Kingdom
⨯
Christopher S. Stevenson,

Affiliations Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Centre for Integrative Mammalian Physiology and Pharmacology, Imperial College London, London, United Kingdom
⨯
Joseph Rastrick,

Affiliation Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Nicole Dale,

Affiliation Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Kristof Raemdonck,

Affiliation Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Sissie Wong,

Affiliation Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Matthew C. Catley,

Affiliation Union Chimique Belge Pharma Ltd, Union Chimique Belge Celltech, Slough, Berkshire, Belgium
⨯
Maria G. Belvisi,

Affiliations Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Centre for Integrative Mammalian Physiology and Pharmacology, Imperial College London, London, United Kingdom
⨯
Mark A. Birrell

* E-mail: m.birrell@imperial.ac.uk

Affiliations Respiratory Pharmacology, Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Centre for Integrative Mammalian Physiology and Pharmacology, Imperial College London, London, United Kingdom
⨯

P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

Suffwan Eltom,
Christopher S. Stevenson,
Joseph Rastrick,
Nicole Dale,
Kristof Raemdonck,
Sissie Wong,
Matthew C. Catley,
Maria G. Belvisi,
Mark A. Birrell

Published: September 6, 2011
https://doi.org/10.1371/journal.pone.0024097

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02 Oct 2011
12:43 GMT
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Figure 4F Posted by mabelvisi on 02 Oct 2011 at 12:43 GMT

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