Genetic Background Strongly Modifies the Severity of Symptoms of Hirschsprung Disease, but Not Hearing Loss in Rats Carrying Ednrb^sl Mutations

• Ruihua Dang,

  Affiliation Laboratory of Animal Science and Medicine, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

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• Daisuke Torigoe,

  Affiliation Laboratory of Animal Science and Medicine, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

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• Sari Suzuki,

  Affiliation Department of Bioproduction, Tokyo University of Agriculture, Abashiri, Japan

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• Yoshiaki Kikkawa,

  Affiliations Department of Bioproduction, Tokyo University of Agriculture, Abashiri, Japan, Mammalian Genetics Project, Tokyo Metropolitan Institute of Medical Science, Tokyo Japan

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• Kanako Moritoh,

  Affiliation Laboratory of Animal Science and Medicine, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

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• Nobuya Sasaki,

  Affiliation Laboratory of Animal Science and Medicine, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

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• Takashi Agui

  * E-mail: agui@vetmed.hokudai.ac.jp

  Affiliation Laboratory of Animal Science and Medicine, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

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