Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates Dendritic Cells through Toll-Like Receptor 4

• Marcelo Hill ,

  * E-mail: mktaha@pasteur.fr (MKT); mhill@nantes.inserm.fr (MH)

  Affiliations INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France, Departamento de Inmunobiologia, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay

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• Ala-Eddine Deghmane,

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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• Mercedes Segovia,

  Affiliation INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France

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• Maria Leticia Zarantonelli,

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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• Gaëlle Tilly,

  Affiliation INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France

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• Philippe Blancou,

  Affiliation Institut National de la Recherche Agronomique, Ecole Nationale Vétérinaire, Université de Nantes, Nantes, France

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• Gaëlle Bériou,

  Affiliation INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France

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• Régis Josien,

  Affiliations INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France, CHU de Nantes, Laboratoire d'Immunologie, Nantes, France

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• Ignacio Anegon,

  Affiliation INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France

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• Eva Hong,

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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• Corinne Ruckly,

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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• Aude Antignac,

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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• Meriem El Ghachi,

  Affiliations Institut Pasteur, Biology and Genetic of Bacterial Cell Wall Group, Paris, France, INSERM, Biology and Genetic of Bacterial Cell Wall Group Avenir, Paris, France

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• Ivo Gomperts Boneca,

  Affiliations Institut Pasteur, Biology and Genetic of Bacterial Cell Wall Group, Paris, France, INSERM, Biology and Genetic of Bacterial Cell Wall Group Avenir, Paris, France

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• Muhamed-Kheir Taha ,

  Contributed equally to this work with: Muhamed-Kheir Taha, Maria Cristina Cuturi

  * E-mail: mktaha@pasteur.fr (MKT); mhill@nantes.inserm.fr (MH)

  Affiliation Institut Pasteur, Invasive Bacterial Infections Unit, Paris, France

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•  [ ... ],
• Maria Cristina Cuturi

  Contributed equally to this work with: Muhamed-Kheir Taha, Maria Cristina Cuturi

  Affiliation INSERM U643, Nantes, CHU de Nantes, IUN, Nantes, Université de Nantes, UMR 643, Nantes, France

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