N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats

Tingting Wang; Shigang Qiao; Shaoqing Lei; Yanan Liu; Kwok F. J. Ng; Aimin Xu; Karen S. L. Lam; Michael G. Irwin; Zhengyuan Xia

doi:10.1371/journal.pone.0023967

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Open Access

Peer-reviewed

Research Article

N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats

Tingting Wang,

Affiliation Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China
⨯
Shigang Qiao,

Affiliation Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China
⨯
Shaoqing Lei,

Affiliation Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China
⨯
Yanan Liu,

Affiliation Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China
⨯
Kwok F. J. Ng,

Affiliations Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China, Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong SAR, China, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China
⨯
Aimin Xu,

Affiliations Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong SAR, China, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China
⨯
Karen S. L. Lam,

Affiliations Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong SAR, China, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China
⨯
Michael G. Irwin ,

* E-mail: zyxia@hku.hk (ZX); mgirwin@hku.hk (MGI)

Affiliations Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China, Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong SAR, China
⨯
Zhengyuan Xia

* E-mail: zyxia@hku.hk (ZX); mgirwin@hku.hk (MGI)

Affiliations Department of Anaesthesiology, The University of Hong Kong, Hong Kong SAR, China, Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong SAR, China
⨯

N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats

Tingting Wang,
Shigang Qiao,
Shaoqing Lei,
Yanan Liu,
Kwok F. J. Ng,
Aimin Xu,
Karen S. L. Lam,
Michael G. Irwin,
Zhengyuan Xia

Published: August 30, 2011
https://doi.org/10.1371/journal.pone.0023967

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