Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

• George M. Philips ,

  Contributed equally to this work with: George M. Philips, Isaac S. Chan

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Isaac S. Chan ,

  Contributed equally to this work with: George M. Philips, Isaac S. Chan

  Affiliations Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Genetics, The University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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• Marzena Swiderska,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Vanessa T. Schroder,

  Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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• Cynthia Guy,

  Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Gamze F. Karaca,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Cynthia Moylan,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Talaignair Venkatraman,

  Affiliation Department of Radiology, Duke University, Durham, North Carolina, United States of America

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• Sebastian Feuerlein,

  Affiliation Department of Radiology, Duke University, Durham, North Carolina, United States of America

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• Wing-Kin Syn,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Youngmi Jung,

  Affiliations Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biological Science, Pusan National University, Pusan, Korea

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• Rafal P. Witek,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Steve Choi,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Gregory A. Michelotti,

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Fatima Rangwala,

  Affiliation Divisions of Cell Therapy, Hematology and Medical Oncology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Elmar Merkle,

  Affiliation Department of Radiology, Duke University, Durham, North Carolina, United States of America

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• Christopher Lascola,

  Affiliation Department of Radiology, Duke University, Durham, North Carolina, United States of America

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•  [ ... ],
• Anna Mae Diehl

  * E-mail: annamae.diehl@duke.edu

  Affiliation Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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