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Open Access
Peer-reviewed
Research Article
Characterisation of Genome-Wide Association Epistasis Signals for Serum Uric Acid in Human Population Isolates
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Wenhua Wei ,
* E-mail: wenhua.wei@hgu.mrc.ac.uk (WHW); chris.haley@hgu.mrc.ac.uk (CSH)
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Gibran Hemani,
Affiliation The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian, United Kingdom
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Andrew A. Hicks,
Affiliation Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany
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Veronique Vitart,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Claudia Cabrera-Cardenas,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Pau Navarro,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Jennifer Huffman,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Caroline Hayward,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Sara A. Knott,
Affiliation Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom
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Igor Rudan,
Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Croatian Centre for Global Health, University of Split, Split, Croatia
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Peter P. Pramstaller,
Affiliations Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany, Department of Neurology, General Central Hospital, Bolzano, Italy, Department of Neurology, University of Lübeck, Lübeck, Germany
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Sarah H. Wild,
Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
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James F. Wilson,
Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
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Harry Campbell,
Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
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Malcolm G. Dunlop,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Nicholas Hastie,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Alan F. Wright,
Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
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Chris S. Haley
* E-mail: wenhua.wei@hgu.mrc.ac.uk (WHW); chris.haley@hgu.mrc.ac.uk (CSH)
Affiliations MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom, The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian, United Kingdom
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Characterisation of Genome-Wide Association Epistasis Signals for Serum Uric Acid in Human Population Isolates
- Wenhua Wei,
- Gibran Hemani,
- Andrew A. Hicks,
- Veronique Vitart,
- Claudia Cabrera-Cardenas,
- Pau Navarro,
- Jennifer Huffman,
- Caroline Hayward,
- Sara A. Knott,
- Igor Rudan
- Published: August 19, 2011
- https://doi.org/10.1371/journal.pone.0023836