The Hedgehog Receptor Patched Is Involved in Cholesterol Transport

Michel Bidet; Olivier Joubert; Benoit Lacombe; Marine Ciantar; Rony Nehmé; Patrick Mollat; Lionel Brétillon; Hélène Faure; Robert Bittman; Martial Ruat; Isabelle Mus-Veteau

doi:10.1371/journal.pone.0023834

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Open Access

Peer-reviewed

Research Article

The Hedgehog Receptor Patched Is Involved in Cholesterol Transport

Michel Bidet,

Affiliation Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France
⨯
Olivier Joubert,

Affiliations Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France, Université Henri Poincaré- Nancy 1, EA 3452, Faculté de Pharmacie, Nancy, France
⨯
Benoit Lacombe,

Affiliation Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France
⨯
Marine Ciantar,

Affiliation Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France
⨯
Rony Nehmé,

Affiliations Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France, Laboratory of Molecular Biology, Medical Research Council (MRC), Cambridge, United Kingdom
⨯
Patrick Mollat,

Affiliation Galapagos SASU, Romainville, France
⨯
Lionel Brétillon,

Affiliation Université de Bourgogne, CNRS-INRA, Centre des Sciences du Goût et de l'Alimentation, Dijon, France
⨯
Hélène Faure,

Affiliation CNRS, UPR-3294, Laboratoire de Neurobiologie et Développement, Institut de Neurobiologie Alfred Fessard IFR2118, Gif-sur-Yvette, France
⨯
Robert Bittman,

Affiliation Department of Chemistry and Biochemistry, Queens College of the City University of New York, Flushing, New York, United States of America
⨯
Martial Ruat,

Affiliation CNRS, UPR-3294, Laboratoire de Neurobiologie et Développement, Institut de Neurobiologie Alfred Fessard IFR2118, Gif-sur-Yvette, France
⨯
Isabelle Mus-Veteau

* E-mail: isabelle.mus-veteau@unice.fr

Affiliation Université de Nice - Sophia Antipolis, CNRS-UMR 6543, Institute of Developmental Biology and Cancer, Nice, France
⨯

The Hedgehog Receptor Patched Is Involved in Cholesterol Transport

Michel Bidet,
Olivier Joubert,
Benoit Lacombe,
Marine Ciantar,
Rony Nehmé,
Patrick Mollat,
Lionel Brétillon,
Hélène Faure,
Robert Bittman,
Martial Ruat

Published: September 8, 2011
https://doi.org/10.1371/journal.pone.0023834

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Cholesterol
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Hedgehog signaling
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Cell membranes
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Yeast
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Saccharomyces cerevisiae
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Membrane proteins
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Fibroblasts
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NIH 3T3 cells
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