Divalent Metal Ion Differentially Regulates the Sequential Nicking Reactions of the GIY-YIG Homing Endonuclease I-BmoI

• Benjamin P. Kleinstiver,

  Affiliation Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada

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• Wesley Bérubé-Janzen,

  Affiliation Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada

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• Andrew D. Fernandes,

  Affiliations Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada, Department of Applied Mathematics, The University of Western Ontario, London, Ontario, Canada

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• David R. Edgell

  * E-mail: dedgell@uwo.ca

  Affiliation Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada

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