Upregulation of Circulating PD-L1/PD-1 Is Associated with Poor Post-Cryoablation Prognosis in Patients with HBV-Related Hepatocellular Carcinoma

Zhen Zeng; Feng Shi; Lin Zhou; Min-Na Zhang; Yan Chen; Xiu-Juan Chang; Yin-Ying Lu; Wen-Lin Bai; Jian-Hui Qu; Chun-Ping Wang; Hong Wang; Min Lou; Fu-Sheng Wang; Ji-Yun Lv; Yong-Ping Yang

doi:10.1371/journal.pone.0023621

Loading metrics

Open Access

Peer-reviewed

Research Article

Upregulation of Circulating PD-L1/PD-1 Is Associated with Poor Post-Cryoablation Prognosis in Patients with HBV-Related Hepatocellular Carcinoma

Zhen Zeng ,

Contributed equally to this work with: Zhen Zeng, Feng Shi, Lin Zhou

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Feng Shi ,

Contributed equally to this work with: Zhen Zeng, Feng Shi, Lin Zhou

Affiliations Research Center for Biological Therapy, Beijing 302 Hospital, Beijing, China, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
⨯
Lin Zhou ,

Contributed equally to this work with: Zhen Zeng, Feng Shi, Lin Zhou

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Min-Na Zhang,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Yan Chen,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Xiu-Juan Chang,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Yin-Ying Lu,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Wen-Lin Bai,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Jian-Hui Qu,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Chun-Ping Wang,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Hong Wang,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Min Lou,

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯
Fu-Sheng Wang,

Affiliation Research Center for Biological Therapy, Beijing 302 Hospital, Beijing, China
⨯
Ji-Yun Lv,

Affiliations Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China, Research Center for Biological Therapy, Beijing 302 Hospital, Beijing, China
⨯
Yong-Ping Yang

* E-mail: yongpingyang@hotmail.com

Affiliation Center of Therapeutic Research for Hepatocellular Carcinoma, Beijing 302 Hospital, Beijing, China
⨯

Upregulation of Circulating PD-L1/PD-1 Is Associated with Poor Post-Cryoablation Prognosis in Patients with HBV-Related Hepatocellular Carcinoma

Zhen Zeng,
Feng Shi,
Lin Zhou,
Min-Na Zhang,
Yan Chen,
Xiu-Juan Chang,
Yin-Ying Lu,
Wen-Lin Bai,
Jian-Hui Qu,
Chun-Ping Wang

Published: September 1, 2011
https://doi.org/10.1371/journal.pone.0023621

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Hepatocellular carcinoma
Is the Subject Area "Hepatocellular carcinoma" applicable to this article?

Thanks for your feedback.
Cryoablation
Is the Subject Area "Cryoablation" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Prognosis
Is the Subject Area "Prognosis" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Pancreatic cancer
Is the Subject Area "Pancreatic cancer" applicable to this article?

Thanks for your feedback.